This means all their major immune genes are just like yours. A sibling or an unrelated donor may be a “full match” for you. By chance, there may be an unrelated person who inherited the same immune genes as you. Our immune genes are also shared by other humans. That’s why our siblings can have an identical pattern of immune genes. These genes are passed on to us from our parents. Examples are a sibling, parent, or child related to you by blood.Īll humans have genes that control how our immune system works. Your donor may be an unrelated person, or a family member. The process of finding a donor is a very important part of your transplant. Will the donor cells need any treatment or changes before they’re infused? If you need an allogeneic transplant, you and your doctor will talk about 2 important decisions: It helps you and your caregivers understand what to expect throughout your transplant journey.

Read our guide to allogeneic stem cell transplants. This procedure is like a blood transfusion and is called infusion. Next, we add the new stem cells to your bloodstream through a tube or port. It also makes some space in the bone marrow for the new donated stem cells. It kills cancer cells and makes it harder for your immune system to reject the donor’s cells. It’s important to have this therapy before a transplant. We may treat the new cells in the lab before we transplant them.īefore your transplant, you will have chemotherapy, or chemotherapy along with radiation therapy.

The new cells can come from an adult donor or from donated umbilical cord blood. This includes red blood cells, white blood cells, and platelets. These transplanted cells then develop into all the parts of the blood and immune system. After they’re transplanted, these cells go to the bone marrow and replace the person’s own stem cells. An allogeneic (A-loh-jeh-NAY-ik) transplant takes healthy blood or bone marrow stem cells from a donor and gives them to another person.

Allogeneic bmt